Spastic paraplegia four (SPG4; also known as SPAST-HSP) is characterised by insidiously progressive bilateral decreased-limb gait spasticity. Over fifty% of impacted persons have some weakness from the legs and impaired vibration sense with the ankles.???? ??? ? ?? ??: ??? ??? ???? ???? ??? ? ????.??? ?? ??: ???? ??? ??? ? ?? ?? ??? ?? ???? ?????.?